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Glutamatergic Tuning of Hyperactive Striatal Projection Neurons Controls the Motor Response to Dopamine Replacement in Parkinsonian Primates
Authors:Arun Singh  Meagan A. Jenkins  Kenneth J. Burke  Goichi Beck  Andrew Jenkins  Annalisa Scimemi  Stephen F. Traynelis  Stella M. Papa
Affiliation:1. Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30329, USA;2. Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA;3. Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA 30322, USA;4. Department of Biology, State University of New York, Albany, NY 12222, USA;5. Department of Neurology, Emory University School of Medicine, Atlanta, GA 30329, USA
Abstract:
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  • Keywords:striatum  striatal projection neuron  SPN  medium spiny neuron  dopamine  glutamate  NMDAR  AMPAR  Parkinson’s disease  dyskinesia
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