The structure and function of Na+ channels. |
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| Authors: | W Stühmer A B Parekh |
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| Institution: | Abteilung Membranebiophysik, Max Planck Institute für Biophysikalische Chemie, G?ttingen, Germany. |
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| Abstract: | The past year has seen major advances in our understanding of voltage-gated ion channels through a powerful combination of patch-clamp and molecular biological techniques. These approaches have identified regions (in some cases single amino acid residues) that are essential for voltage-dependent activation and inactivation, lining of the pore, and regulation of channel function. |
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