The inner compass of spindle positioning and orientation |
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| Authors: | Fong Chii Shyang Tsou Meng-Fu Bryan |
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| Institution: | Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. |
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| Abstract: | Polarized cortical cues are known to guide spindle movements to dictate division axis and cleavage site during asymmetric cell division. In a recent issue of Nature Cell Biology, Kiyomitsu and Cheeseman (2012) report two novel spindle-intrinsic signals that regulate spindle orientation and position in symmetrically dividing human cells. |
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