ATIA: a link between inflammation and hypoxia |
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| Authors: | Lin Anning |
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| Affiliation: | Ben May Department for Cancer Research, University of Chicago, Chicago, IL 80637, USA. anninglin@bsd.uchicago.edu |
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| Abstract: | In this issue of Molecular Cell,Choksi et al. (2011) report the identification of an NF-κB-independent ATIA (anti-TNFα-induced apoptosis)-Thioredoxin 2 axis that inhibits TNFα- and hypoxia-induced apoptosis through elimination of excessive reactive oxygen species directly. |
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