Functional aspects of the ventral pallidum |
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Authors: | B D Kretschmer |
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Institution: | (1) Department of Neuropharmacology, University of Tübingen Federal, Republic of Germany, DE |
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Abstract: | Summary. The ventral pallidum is part of the corticoaccumbo-thalamocortical loop of the basal ganglia. In the past the function of
this structure was discussed as a pure relay station in the process of limbic-motor integration. Some recent studies, however,
underline that on the level of the ventral pallidum motor behavior can be modulated. The stimulation and inhibition of the
different transmitter systems that converge in the ventral pallidum (dopamine, glutamate, GABA, neuropeptides) have implications
in repetitive-, disinhibited-, learning- and reinforced behavior. The present review summarizes available data of these parameter
related to this behavior, i.e. locomotion, reward-related behavior, prepulse inhibition, memory and neurochemistry.
Received August 31, 1999 Accepted September 20, 1999 |
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Keywords: | : Amino acids Ventral pallidum Corticoaccumbo-thal-amocortical loop Locomotion Reward Prepulse inhibition Memory Microdialysis |
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