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Biomarkers of Lead Exposure Among a Population Under Environmental Stress
Authors:Yonghua Li  Biao Zhang  Hairong Li  Linsheng Yang  Bixiong Ye  Wuyi Wang  Mark Rosenberg
Affiliation:1. Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, 11A Datun Road, Chaoyang District, Beijing, 100101, China
2. Institute of Environmental Health and Related Product Safety, Beijing, 100021, China
3. Department of Geography, Queen’s University, Kingston, K7L 3N6, Canada
Abstract:This study aimed to evaluate the relationship between blood lead and serum creatinine and blood lead and serum urea nitrogen levels as biomarkers of lead exposure from subjects living in a historic polymetallic mining area in China. Elevated levels were found for blood lead, serum creatinine, and serum urea nitrogen in the mining area with mean values at 245.65 μg/l, 74.16 μmol/l, and 12.79 mmol/l, which were significantly higher than those in the control area, respectively. Moreover, the coefficients between paired results for blood lead and serum creatinine and blood lead and serum urea nitrogen were positively statistically significant (serum creatinine vs. blood lead, r?=?0.35, p?r?=?0.48, p?
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