Wound healing: GTPases flux their muscles |
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| Authors: | Bedra Sharif Amy Shaub Maddox |
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| Affiliation: | Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. |
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| Abstract: | An article by Houk et al. (2012) in Cell provides insight into the mechanisms confining membrane protrusions to the front of migrating neutrophils. The authors rule out a role for diffusion of inhibitory signals and show that membrane tension is necessary and sufficient to restrict signals that lead to protrusions. |
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