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Profile of cancer in the Eastern Mediterranean region: The need for action
Affiliation:1. Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France;2. WHO, Regional Office of the Eastern Mediterranean, Cairo, Egypt;3. King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia;4. Epidemiology and Cancer Registry Department, Kuwait Cancer Control Center, Kuwait;5. Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt;6. King Hussein Cancer Center, Amman, Jordan;7. Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon;1. Department of Epidemiology, Fielding School of Public Health, University of California, CA, USA;2. Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA;3. Division of Pediatric Hematology/Oncology, Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA;1. University of Tampere, School of Health Sciences, Tampere, Finland;2. Department of Clinical Chemistry, Helsinki University Central Hospital, Finland;3. Tampere University Hospital, Department of Urology and University of Tampere, Medical School, Tampere, Finland;4. Department of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands;5. Sahlgrenska Academy at Göteborg University, Gothenburg, Sweden;6. Memorial Sloan-Kettering Cancer Centre, Department of Surgery and Department of Epidemiology and Biostatistics, New York, NY, USA;7. Finnish Cancer Registry, Helsinki, Finland;1. Yale School of Public Health, New Haven, CT, 06520, United States;2. Yale Cancer Center, New Haven, CT, 06520, United States;3. UCSF Departments of Neurological Surgery and Epidemiology and Biostatistics, San Francisco, CA 94143, United States;4. Yale University School of Medicine, New Haven, CT 06520, United States;1. Primary Care Research Unit of Mallorca, Baleares Health Services-IbSalut, 07005 Palma, España, Instituto de Investigación Sanitaria de Palma, 07010 Palma, Spain;2. Evaluation and Clinical Epidemiology Department, Hospital del Mar, Passeig Marítim 25-29, 08003, Barcelona, Spain;3. Clinical Epidemiology and Biostatistics Unit, A Coruña University, Complexo Hospitalario Universitario A Coruña, Xubias de Arriba, 84, Hotel de los pacientes 7ª planta, 15006, A Coruña, Spain;4. Serreria II Primary Care Centre, Valencia Institute of Health, C/Pedro de Valencia 28, 46022, Valencia, Spain;5. Canal Imperial Primary Care Centre, Paseo Colon 4, Zaragoza, 50006, Spain;6. Department of Public Health, Balearic Department of Health, C/Jesus n 33, 07001, Instituto de Investigación Sanitaria de Palma, 07010 Palma, Spain, Spain;1. University of Sydney, Australia;2. University of New South Wales, Australia
Abstract:BackgroundMany countries in the Eastern Mediterranean region (EMR) are undergoing marked demographic and socioeconomic transitions that are increasing the cancer burden in region. We sought to examine the national cancer incidence and mortality profiles as a support to regional cancer control planning in the EMR.MethodsGLOBOCAN 2012 data were used to estimate cancer incidence and mortality by country, cancer type, sex and age in 22 EMR countries. We calculated age-standardized incidence and mortality rates (per 100,000) using direct method of standardization.ResultsThe cancer incidence and mortality rates vary considerably between countries in the EMR. Incidence rates were highest in Lebanon (204 and 193 per 100,000 in males and females, respectively). Mortality rates were highest in Lebanon (119) and Egypt (121) among males and in Somalia (117) among females. The profile of common cancers differs substantially by sex. For females, breast cancer is the most common cancer in all 22 countries, followed by cervical cancer, which ranks high only in the lower-income countries in the region. For males, lung, prostate, and colorectal cancer in combination represent almost 30% of the cancer burden in countries that have attained very high levels of human development.ConclusionsThe most common cancers are largely amenable to preventive strategies by primary and/or secondary prevention, hence a need for effective interventions tackling lifestyle risk factors and infections. The high mortality observed from breast and cervical cancer highlights the need to break the stigmas and improve awareness surrounding these cancers.
Keywords:Cancer  Mortality  Incidence  Risk factors  Eastern Mediterranean region
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