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蒽醌衍生物结构及其对小麦白粉病菌生物活性的关系研究
引用本文:喻大昭,杨立军,杨小军,倪汉文,曾凡松,向礼波,汪华.蒽醌衍生物结构及其对小麦白粉病菌生物活性的关系研究[J].天然产物研究与开发,2009,21(5):837-839.
作者姓名:喻大昭  杨立军  杨小军  倪汉文  曾凡松  向礼波  汪华
作者单位:1. 湖北省农科院植保土肥研究所,武汉,430064
2. 中国农业大学农学与生物技术学院,北京,100193
基金项目:国家"十一五"支撑计划(2006BAD08A05):农业部行业计划专项,湖北省农科院创新项目 
摘    要:蒽醌衍生物是植物产生的一类次生代谢产物,对植物病原真菌具有明显的活性。为明确蒽醌衍生物结构与其生物活性之间的关系,以小麦白粉病菌为研究对象,测定了蒽醌及16种蒽醌衍生物对该病菌的活性。结果表明,蒽醌衍生物对小麦白粉病菌的活性明显大于葸醌的活性;甲氧基的位置与活性关系密切,6位是决定活性的关键,活性顺序为5、6位〉1、6位〉6位〉8位。

关 键 词:蒽醌衍生物  结构  生物活性

Relationship between Anthraquinone Derivatives Structure and Its Activity against Blumera graminis
YU Da-zhao,YANG Li-jun,YANG Xiao-jun,NI Han-wen,ZENG Fan-song,XIANG Li-bo,WANG Hua.Relationship between Anthraquinone Derivatives Structure and Its Activity against Blumera graminis[J].Natural Product Research and Development,2009,21(5):837-839.
Authors:YU Da-zhao  YANG Li-jun  YANG Xiao-jun  NI Han-wen  ZENG Fan-song  XIANG Li-bo  WANG Hua
Abstract:Anthraquinone derivatives are a class of secondary metabolites produced by plant,which have obvious activities against the plant pathogenic fungus. To clear the relationship between the structure of anthraquinone derivatives and its biological activity,anthraquinone and 16 anthraquinone derivatives were tested against Blumera graminis f. Sp. Tritici. The results showed that the activity of anthraquinone derivative was more effective than that of anthraquinone. The position of methoxy showed a close correlation with its activity. The sixth is the key position of methoxywith and the activity with the order of 5,6- > 1,6- > 6 > 8.
Keywords:anthraquinone derivatives  structure  biological activity
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