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An Adaptive Location‐Scale Test
Authors:Markus Neuhuser
Abstract:Increasing locations are often accompanied by an increase in variability. In this case apparent heteroscedasticity can indicate that there are treatment effects and it is appropriate to consider an alternative involving differences in location as well as in scale. As a location‐scale test the sum of a location and a scale test statistic can be used. However, the power can be raised through weighting the sum. In order to select values for this weighting an adaptive design with an interim analysis is proposed: The data of the first stage are used to calculate the weights and with the second stage's data a weighted location‐scale test is carried out. The p‐values of the two stages are combined through Fisher's combination test. With a Lepage‐type location‐scale test it is illustrated that the resultant adaptive test can be more powerful than the ‘optimum’ test with no interim analysis. The principle to calculate weights, which cannot be reasonably chosen a priori, with the data of the first stage may be useful for other tests which utilize weighted statistics, too. Furthermore, the proposed test is illustrated with an example from experimental ecology.
Keywords:Adaptive interim analysis  Fisher's combination test  Lepage's test  Weighted test statistics
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