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Gas chromatographic—mass spectrometric methods of analysis for detection of 11-nor-Δ-tetrahydrocannabinol-9-carboxylic acid in biological matrices |
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| Authors: | William E Bronner Allan S Xu |
| Institution: | Armed Forces Institute of Pathology, Division of Forensic Toxicology, Washington, DC 20306-6000 USA Harris Laboratories Inc., Phoenix, AZ 85034 USA |
| Abstract: | Gas chromatographic—mass spectrometric methods of analysis for the detection of 11-nor-Δ9-tetrahydrocinnabinol-9-carboxylic acid, a major metabolite of Δ9-tetrahydrocannabinol, are reviewed. Emphasis is on analytical methodology including numerous derivatization techniques developed specifically for this analyte. The majority of procedures cited in the literature were developed to detect this metabolite in the blood and urine of man. |
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