Luxury accommodations: the expanding role of structural plasticity in protein-protein interactions |
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Authors: | Sundberg E J Mariuzza R A |
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Affiliation: | Center for Advanced Research in Biotechnology, University of Maryland, Biotechnology Institute, Rockville, MD 20850, USA. |
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Abstract: | The recognition of multiple ligands at a single molecular surface is essential to many biological processes. Conformational flexibility has emerged as a compelling strategy for association at such convergent binding sites. Studies over the past few years have brought about a greater understanding of the role that protein plasticity might play in protein-protein interactions. |
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