Use of serial analysis of gene expression to reveal the specific regulation of gene expression profile in asthmatic rats treated by acupuncture |
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| Authors: | Lei-Miao Yin Gong-Hao Jiang Yu Wang Yan Wang Yan-Yan Liu Wei-Rong Jin Yu-Dong Xu Qing-Hua Zhang Yong-Qing Yang |
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| Affiliation: | (1) Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai, PR, China;(2) National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology & Ecology, Chinese Academy of Sciences, Shanghai, PR, China;(3) National Engineering Center for Biochips at Shanghai, Shanghai, PR, China |
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| Abstract: | Background Asthma has become an important public health issue and approximately 300 million people have suffered from the disease worldwide. Nowadays, the use of acupuncture in asthma is increasing. This study intended to systematically analyze and compare the gene expression profiles between the asthmatic and acupuncture-treated asthmatic rat lung, and tried to gain insight into the molecular mechanism underlying the early airway response (EAR) phase of asthma treated by acupuncture. |
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