Effects of benzylpenicillin on glucose utilization, macromolecule synthesis and cell wall proteins of Listeria monocytogenes |
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Authors: | L.-J. Chen J. Wang R.E. Levin |
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Affiliation: | Department of Food Science, Agricultural Experiment Station, University of Massachusetts, Amherst, MA, USA |
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Abstract: | L.-J. CHEN, J. WANG AND R.E. LEVIN. 1996. When growing cells were incubated in the presence of 100 ppm benzylpenicillin (BP) for 30 min and then harvested for metabolic studies, the initial rate of glucose utilization by resting cells was reduced by 19.6% compared to control cells, whereas the rates of protein, DNA and RNA synthesis were reduced by 40.7%, 55.0% and 87.5% respectively. Growth in the presence of 100 ppm BP for 2 h was found to result in a marked depletion of cell wall proteins. |
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