A necdin/MAGE-like gene in the chromosome 15 autism susceptibility region: expression, imprinting, and mapping of the human and mouse orthologues |
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Authors: | Thea K Chibuk Jocelyn M Bischof Rachel Wevrick |
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Institution: | (1) Department of Medical Genetics, University of Alberta, Edmonton, Alberta, Canada |
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Abstract: | Background Proximal chromosome 15q is implicated in neurodevelopmental disorders including Prader-Willi and Angelman syndromes, autistic disorder and developmental abnormalities resulting from chromosomal deletions or duplications. A subset of genes in this region are subject to genomic imprinting, the expression of the gene from only one parental allele. |
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