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Traumatic brain injury as a risk factor for Alzheimer disease. Comparison of two retrospective autopsy cohorts with evaluation of ApoE genotype |
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| Authors: | Kurt A Jellinger Werner Paulus Christian Wrocklage Irene Litvan |
| Institution: | (1) L.Boltzmann Institute of Clinical Neurobiology, Baumgartner Hoehe 1, B-Bldg, A-1140, Vienna, Austria;(2) Department of Neuropathology, University of Munster School of Medicine, Munster, Germany;(3) Cognitive Neuropharmacology Unit, H.M. Jackson Foundation, Bethesda, Md, USA |
| Abstract: | Background and PurposeThe impact of traumatic brain injury (TBI) on the pathogenesis of Alzheimer disease (AD) is still controversial. The aim of our retrospective autopsy study was to assess the impact of TBE and ApoE allele frequency on the development of AD. |
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