| Abstract: | A new pimarane diterpenoid, named botryopimarene A ( 1 ), was discovered from the fungus Botryotinia fuckeliana MCCC 3 A00494 isolated from the deep‐sea water, together with ten known compounds. The planar structure of 1 was established based on the extensive spectroscopic analyses. The absolute configurations of tricyclic system in 1 were resolved by the theoretical ECD calculation, while the 15,16‐diol moiety in the side chain was resolved by the Mo2(OAc)4‐induced ECD spectrum. Compound 1 , featuring a Δ9(11) double bond, was rarely discovered in pimarane family. Compounds 1 – 11 were tested for their cytotoxic activities using six human cancer cell lines by the MTT method. However, none of the compounds exhibited detectable cytotoxicities (IC50 >20 μm ). |
