Induction of aldose reductase and polyol dehydrogenase activities in Aureobasidium pullulans by d-xylose,l-arabinose and d-galactose

Summary The induction of aldose reductase and polyol dehydrogenase activities by d-xylose, l-arabinose, d-galactose and d-glucose was studied in the yeast-like organism Aureobasidium pullulans CCY 27-1-26. d-xylose and l-arabinose induced two distinct NADPH-dependent aldose reductases and the inducing saccharide was simultaneously the most efficient substrate for the corresponding enzymatic reaction. Polyol dehydrogenase induced by d-xylose, l-arabinose and d-galactose was strictly NAD⁺-dependent and required only xylitol as a substrate of the enzymatic reaction. l-Arabitol did not act as a substrate for l-arabinose-induced polyol dehydrogenase either in the presence of NAD⁺ or NADP⁺.