Questions regarding the predictive value of one evolved complex adaptive system for a second: Exemplified by the SOD1 mouse |
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| Authors: | Ray Greek Lawrence A. Hansen |
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| Affiliation: | 1. Americans for Medical Advancement, 2251 Refugio Road, Goleta, CA 93117, USA;2. University of California, San Diego, Department of Neurosciences, Mail Code 062 9500, Gilman Drive (MTF 351), La Jolla, CA 92093-0624, USA |
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| Abstract: | We surveyed the scientific literature regarding amyotrophic lateral sclerosis, the SOD1 mouse model, complex adaptive systems, evolution, drug development, animal models, and philosophy of science in an attempt to analyze the SOD1 mouse model of amyotrophic lateral sclerosis in the context of evolved complex adaptive systems. |
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| Keywords: | ALS Animal models Complex systems Evolution Predictive value SOD1 mouse |
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