| 广西仫佬族Y染色体和mtDNA的遗传结构分析 |
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| 引用本文： | 王晓庆,王传超,邓琼英,李辉.广西仫佬族Y染色体和mtDNA的遗传结构分析[J].遗传,2013,35(2):168-174. |
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| 作者姓名： | 王晓庆 王传超 邓琼英 李辉 |
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| 作者单位： | 1. 广西医科大学基础医学院, 南宁 2. 复旦大学生命科学学院现代人类学教育部重点实验室, 上海 200433 |
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| 基金项目： | 广西自然科学基金资助项目(编号:2011GXNSFA018240)资助 |
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| 摘 要： | 文章对我国广西仫佬族91个无关男性个体Y-STR、Y-SNP、mtDNA HVS-Ⅰ和mtDNA-SNP等进行检测分型, 探索仫佬族的分子遗传结构。结果显示：Y染色体单倍群O1a1-P203和O2a1*-M95在仫佬族中为高频单倍群, 利用Y-STR构建的N-J树中仫佬族与侗族聚类, 说明在父系遗传上仫佬族与侗族遗传关系较近; mtDNA中F1a、M*、B4a、B5a等4类单倍群高频出现, 体现出仫佬族在母系遗传方面具有典型的东亚南方群体特征。17个Y-STR位点和mtDNA HVS-Ⅰ具有丰富的遗传多态性, 在群体遗传学和法医学方面具有应用前景。
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| 关 键 词： | 仫佬族 Y-STR Y-SNP mtDNA 遗传结构 |
| 收稿时间： | 2012-05-07 |
Genetic analysis of Y chromosome and mitochondrial DNA polymorphism of Mulam ethnic group in Guangxi,China |
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| WANG Xiao-Qing,WANG Chuan-Chao,DENG Qiong-Ying,LI Hui.Genetic analysis of Y chromosome and mitochondrial DNA polymorphism of Mulam ethnic group in Guangxi,China[J].Hereditas,2013,35(2):168-174. |
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| Authors: | WANG Xiao-Qing WANG Chuan-Chao DENG Qiong-Ying LI Hui |
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| Institution: | 1. Department of Anatomy, Guangxi Medical University, Nanning 530021, China 2. MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200433, China |
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| Abstract: | In order to study the molecular genetic structure of Mulam ethnic group in Guangxi, China, Y chromosome and mitochondrial DNA(mtDNA)polymorphisms were genotyped. High frequencies of the Y chromosome haplogroups O1a1-P203 and O2a1*-M95 were found in Mulam, exhibiting a pattern similar to the neighboring indigenous populations, especially the Daic populations. MtDNA lineages F1a, M*, B4a, B5a, M7b, and N9a were found in Mulam, which always present at high frequencies among the populations of East Asia. Mulam exhibits genetic characteristics of southern Chinese in both paternal and maternal lineages. Multiplex detection of the 17 Y-STR loci and mtDNA HVS-I revealed the distribu-tion of highly genetic diversity in Mulam, which would have potential application in population genetics and forensic practice. |
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| Keywords: | Mulam ethnic group Y-STR Y-SNP mtDNA genetic structure |
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