HISTAMINE-DEPENDENT FORMATION OF N-ACETYL-ASPARTYL PEPTIDES IN MOUSE BRAIN |
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Authors: | K L Reichelt E Kvamme |
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Institution: | Department of Neurochemistry, The Oslo University Psychiatric Clinic, Vinderen, Oslo 3, Norway |
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Abstract: | Abstract— The formation of N -acetyl-aspartyl-peptides in mouse brain homogenates is described. The formation is completely dependent on histamine and on an ATP-regenerating system, and partially dependent on the addition of N -acetyl-aspartate and certain other amino acids. The N -acetyl-aspartyl-peptide formation is probably non-ribosomal and is apparently not due to hydrolysis of preformed proteins. |
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