| 固醇调节元件结合蛋白与炎症的关系研究进展 |
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| 引用本文： | 盘艳君,王燕,徐建强,吴剑锋,喻思扬,曾高峰,赵国军.固醇调节元件结合蛋白与炎症的关系研究进展[J].生物化学与生物物理进展,2016,43(12):1146-1153. |
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| 作者姓名： | 盘艳君 王燕 徐建强 吴剑锋 喻思扬 曾高峰 赵国军 |
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| 作者单位： | 南华大学附属第二医院心血管内科，衡阳 421001,南华大学附属第二医院麻醉科，衡阳 421001,南华大学附属第二医院心血管内科，衡阳 421001,南华大学附属第二医院心血管内科，衡阳 421001,中南大学湘雅二医院心血管内科，长沙 410011,南华大学附属第二医院心血管内科，衡阳 421001,桂林医学院组织胚胎学教研室，桂林 541004 |
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| 基金项目： | 湖南省自然科学基金资助项目(14JJ5016) |
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| 摘 要： | 固醇调节元件结合蛋白(SREBPs)是重要的核转录因子,其主要作用是通过激活胆固醇、脂肪酸和甘油三脂(TG)合成及摄取的相关基因,维持体内脂质代谢的平衡.近年来有研究表明,SREBPs与炎症关系紧密,一方面,SREBPs可以促进炎症的发生和发展,另一方面,炎症可以影响SREBPs的表达,造成脂质代谢紊乱.深入研究SREBPs与炎症的关系,有助于为炎症与脂质代谢紊乱所致相关疾病的防治提供新的方向.
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| 关 键 词： | 固醇调节元件结合蛋白，炎症，脂质代谢 |
| 收稿时间： | 2016/7/17 0:00:00 |
| 修稿时间： | 2016/10/25 0:00:00 |
Advance in The Relationship Between Sterol Regulatory Element-binding Proteins and Inflammation |
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| PAN Yan-Jun,WANG Yan,XU Jian-Qiang,WU Jian-Feng,YU Si-Yang,ZENG Gao-Feng and ZHAO Guo-Jun.Advance in The Relationship Between Sterol Regulatory Element-binding Proteins and Inflammation[J].Progress In Biochemistry and Biophysics,2016,43(12):1146-1153. |
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| Authors: | PAN Yan-Jun WANG Yan XU Jian-Qiang WU Jian-Feng YU Si-Yang ZENG Gao-Feng and ZHAO Guo-Jun |
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| Institution: | Department of Cardiovascular Medicine, The Second Affiliated Hospital of University of South China, Hengyang 421001, China,Department of Anesthesiology, The Second Affiliated Hospital of University of South China, Hengyang 421001, China,Department of Cardiovascular Medicine, The Second Affiliated Hospital of University of South China, Hengyang 421001, China,Department of Cardiovascular Medicine, The Second Affiliated Hospital of University of South China, Hengyang 421001, China,Department of Cardiovascular Medicine, The Second Xiangya Hospital of Central South University, Changsha 410011, China,Department of Cardiovascular Medicine, The Second Affiliated Hospital of University of South China, Hengyang 421001, China and Department of Histology and Embryology, Guilin Medical University, Guilin 541004, China |
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| Abstract: | |
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| Keywords: | sterol regulatory element-binding protein inflammation lipid metabolism |
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