Immunochemical studies on shigella dysenteriae type 9 bacterial polysaccharide |
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Authors: | Jitendranath Pal Sumanta Basu Chintala VN Rao |
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Institution: | Department of Macromolecules, Indian Association for the Cultivation of Science, Calcutta-700032, India |
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Abstract: | On graded hydrolysis and Smith degradation, the O-somatic polysaccharide isolated from Shigella dysenteriae type 9 bacteria, strain NCTC 7919, yielded five oligosaccharides which were characterized. The positions of the O-acetyl and pyruvic acetal groups in the repeating unit were identified. Immunochemical studies indicated that d-galactose is the immunodominant sugar in the polysaccharide, and one of the oligomers, having the structure Gal-(1→3)-GlcNAc-(1→3)-Gal-(1→4)-Man, showed maximum inhibition of the homologous precipitation. |
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