An auto-inhibitor of zygote giant cell formation in Dictyostelium discoideum |
| |
| Authors: | Danton H O'Day Stephen P Szabo Abdul H Chagla |
| |
| Institution: | Department of Zoology and Erindale College, University of Toronto, Mississauga, Ont., Canada, L5L 1C6 |
| |
| Abstract: | The first observable event of sexual development in mated cultures (NC4x V12) of Dictyostelium discoideum is the appearance of zygote giant cells which are the product of cell fusions. The increase in the number of giant cells, which begins at about 21 h, is complete by 28 h. In this paper we show that a low molecular weight auto-inhibitor of zygote giant cell formation is present in 28-h cultures. The data presented suggest that this auto-inhibitor is a natural regulator of sexual development in D. discoideum. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
