Epithelial migration: open your eyes to c-Jun |
| |
| Authors: | Grose Richard |
| |
| Institution: | Viral Carcinogenesis Laboratory, Cancer Research UK London Research Institute, 61 Lincoln's Inn Fields, WC2A 3PX, London, UK. richard.grose@cancer.org.uk |
| |
| Abstract: | Tissue-specific removal of c-jun from epidermal cells in mice leads to a failure of eyelid fusion during embryogenesis and reveals roles for c-Jun in wound repair and tumorigenesis in adult skin. This has provided a definitive test of the in vivo function of AP-1 signalling and shown that EGF signalling is key to all of c-Jun's roles in the epidermis. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
