Induced changes in the affinity of 1,25-dihydroxyvitamin D3 receptors in chick intestine |
| |
| Authors: | A Bar J Rosenberg S Hurwitz |
| |
| Institution: | 1. Laboratory of Cellular and Developmental Biology, National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20205, USA;2. Cellular Metabolism and Obesity Section, National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20205, USA |
| |
| Abstract: | The contents of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) in plasma and intestinal mucose were increased by dietary calcium and by dietary phosphorus restriction. The concentration of intestinal occupied receptors for 1,25(OH)2D3 was higher in calcium-restricted birds. The affinity (association constant) of intestinal receptors for 1,25(OH)2D3 was lower in phosphorus-restricted chicks, as compared to control or calcium-restricted chicks. The number of binding sites were not influenced by dietary calcium or phosphorus restriction. |
| |
| Keywords: | Adipocyte Glucose transporter Insulin Photoaffinity labeling SDS—PAGE sodium dodecyl sulfate polyacrylamide gel electrophoresis |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
