A large palindrome with interchromosomal gene duplications in the pericentromeric region of the D. melanogaster Y chromosome |
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Authors: | Méndez-Lago María Bergman Casey M de Pablos Beatriz Tracey Alan Whitehead Siobhan L Villasante Alfredo |
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Institution: | Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain. |
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Abstract: | The non-recombining Y chromosome is expected to degenerate over evolutionary time, however, gene gain is a common feature of Y chromosomes of mammals and Drosophila. Here, we report that a large palindrome containing interchromosomal segmental duplications is located in the vicinity of the first amplicon detected in the Y chromosome of D. melanogaster. The recent appearance of such amplicons suggests that duplications to the Y chromosome, followed by the amplification of the segmental duplications, are a mechanism for the continuing evolution of Drosophila Y chromosomes. |
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