The ins and outs of heterochromatic DNA repair |
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| Authors: | Peterson Craig L |
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| Affiliation: | Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA. craig.peterson@umassmed.edu |
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| Abstract: | Repetitive DNA is often packaged into heterochromatin structures that prevent illicit recombination events that cause genomic instability. A recent study by Chiolo et?al. (2011) published in Cell finds that DNA double-strand breaks formed within heterochromatin are shuttled to adjacent sites that are "safe" to complete repair by recombination. |
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