Electrochemiluminescence of tris(2,2′‐bipyridyl)ruthenium and its applications in bioanalysis: a review |
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| Authors: | Erkang Wang |
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| Institution: | State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, , Changchun, Jilin, People's Republic of China |
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| Abstract: | Electrochemiluminescence (ECL) of tris(2,2’‐bipyridyl)ruthenium(II) Ru(bpy)32+] is an active research area and includes the synthesis of ECL‐active materials, mechanistic studies and broad applications. Extensive research has been focused on this area, due to its scientific and practical importance. In this mini‐review we focus on the bio‐related applications of ECL. After a brief introduction to Ru(bpy)32+ ECL and its mechanisms, its application in constructing an effective bioassay is discussed in detail. Three types of ECL assay are covered: DNA, immunoassay and functional nucleic acid sensors. Finally, future directions for these assays are discussed. Copyright © 2011 John Wiley & Sons, Ltd. |
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| Keywords: | electrochemiluminescence tris(2 2′ ‐bipyridyl)ruthenium (II) applications |
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