New pyrrole derivatives as antimycobacterial agents analogs of BM212 |
| |
| Authors: | Biava M Fioravanti R Porretta G C Deidda D Maullu C Pompei R |
| |
| Affiliation: | Dipartimento di Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, Università La Sapienza, Rome, Italy. Biava@axrma.uniroma1.it |
| |
| Abstract: | During the course of our investigations in the field of azole antimicrobial agents, we have identified BM212 a pyrrole derivative with good in vitro activity against mycobacteria and candidae. These findings prompted us to prepare new pyrrole derivatives 2-6 in the hope of increasing the activity. The microbiological data showed interesting in vitro activity against Mycobacterium tuberculosis and atypical mycobacteria. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
