| 昆虫对Ｂt毒素的抗性机理研究进展 |
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| 引用本文： | 谭声江,陈晓峰,李典谟.昆虫对Ｂt毒素的抗性机理研究进展[J].昆虫知识,2001,38(1):12-17. |
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| 作者姓名： | 谭声江 陈晓峰 李典谟 |
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| 作者单位： | 中国科学院动物研究所, |
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| 基金项目： | 瑞典国际科学基金!IFS- C/2 36 6 - 2，农业虫鼠害综合治理研究国家重点实验室开放研究基金 -9915项目资助 |
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| 摘 要： | 文中综述了昆虫对苏云杆菌（Ｂt)毒素产生抗性的生化遗传机理及抗性的遗传及交叉抗性情况。昆虫对Ｂt毒素的抗性可能在６个环节发生，其中与毒素特异结合的受体上结合位点的改变及毒素水解过程中的变化是抗性产的两个主要环节。从现有的研究结果来看，实验室及田间抗性昆虫品系对Ｂt毒素产生的抗性主要与昆虫中肠上皮细胞膜上Ｂt毒素特异结合受体的变化有关，深入研究是昆虫对Ｂt毒素的抗性机理，将有助于建立抗性的早期监测技术、抗性治理措施，实施无公害Ｂt农药及转Ｂt基因作物的持续利用。
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| 关 键 词： | 苏云金杆菌 抗性 机理 结合位点 水解过程 昆虫 生化遗传机理 |
| 修稿时间： | 1999年9月16日 |
Research progresses on mechanism of insect resistance to Bacillus thuringiensis toxin. |
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| TAN ShengJiang,CHEN Xiao-Feng,LI Dian-Mo.Research progresses on mechanism of insect resistance to Bacillus thuringiensis toxin.[J].Entomological Knowledge,2001,38(1):12-17. |
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| Authors: | TAN ShengJiang CHEN Xiao-Feng LI Dian-Mo |
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| Abstract: | The current knowledge of biochemical and genetic mechanisms of insect resistance to Bacillus thuringiensis toxin is reviewed. Six potential steps concerning the occurrence of resistance are suggested. Available information on resistance inheritance and cross\|resistance is provided. Binding site modification and altered proteolytic processing are involved in most cases of resistance. From the available information it seems that binding site modification is the most significant resistance mechanism in the field and laboratory resistant strains. Studying the mechanism of insect resistance to Bacillus thuringiensis toxin will provide more toxin selection, wider utilization, and longer durability in integrated pest management programs that utilize Bt toxin and Bt crops. |
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| Keywords: | Bacillus thuringiensis resistance mechanism binding site proteolytic processing |
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