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Dual promoter lentiviral vector generates transgenic mice expressing E2-CSFV glycoprotein in their milk, but impairs early identification of transgenic embryos
Authors:Ramos Oliberto Sánchez  Carratalá Yanet Prieto  Puerta Silvia Gómez  Pereira Natalie C Parra  Amarán Lester Suárez  Chaves Silvana P Jimenez  Alonso Jorge R Toledo
Institution:a Department of Pharmacology, Faculty of Biological Sciences, University of Concepción, Chile
b Galactous Biotech Ltda, Concepción, Chile
c Animal Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), Havana, Cuba
d Department of Physiopathology, Faculty of Biological Sciences, University of Concepción, Chile
e Laboratory of Gene Therapy of Viral Hepatitis, Division of Gene Therapy and Hepatology, Center for Applied Medical Research (CIMA), Pamplona, Navarra, Spain
Abstract:
Keywords:Lentiviral vector  Transgenic mice  Lentiviral transgenesis  Promoter interference  E2 CSFV
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