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mTOR Inhibition Ameliorates Cognitive and Affective Deficits Caused by Disc1 Knockdown in Adult-Born Dentate Granule Neurons
Authors:Miou Zhou,Weidong Li,Shan Huang,Juan Song,Ju   Young Kim,Xiaoli Tian,Eunchai Kang,Yoshitake Sano,Cindy Liu,J. Balaji,Shumin Wu,Yu Zhou,Ying Zhou,Sherveen   N. Parivash,Dan Ehninger,Lin He,Hongjun Song,Guo-li Ming,Alcino   J. Silva
Affiliation:1. Departments of Neurobiology, Psychology, and Psychiatry, Integrative Center for Learning and Memory and Brain Research Institute, UCLA, Los Angeles, CA 90095, USA;2. Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200240, China;3. Wuxi Mental Health Center, 156 Qian Rong Road, Wuxi 214151, China;4. Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA;5. Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA;6. Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;7. Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;8. Human Genetics Program, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;9. Department of Physiology, Medical College of Qingdao University, Qingdao 266071, China
Abstract:
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