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Inhibition of C298S mutant of human aldose reductase for antidiabetic applications: Evidence from in silico elementary mode analysis of biological network model |
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| Authors: | Saif Khan Tulika Bhardwaj Pallavi Somvanshi Raju K. Mandal Sajad A. Dar Arshad Jawed Mohd Wahid Naseem Akhter Mohtashim Lohani S. Alouffi Shafiul Haque |
| Affiliation: | 1. Department of Clinical Laboratory Science, College of Applied Medical Sciences, University of Ha'il, Ha'il, Saudi Arabia;2. Department of Biotechnology, TERI School of Advanced Studies, New Delhi, India;3. Research and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan, Saudi Arabia;4. Faculty of Applied Medical Sciences, Department of Laboratory Medicine, Albaha University, Albaha, Saudi Arabia |
| Abstract: | |
| Keywords: | aldose reductase C298S inhibitors diabetes elementary flux mode analysis metabolic pathway analysis mathematical modeling mutant |