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Apolipoprotein Complexity in Japanese Eel Anguilla japonica: Truncated Apolipoprotein A-I and Apolipoprotein A-I-like Protein in Plasma Lipoproteins
Abstract:A truncated apolipoprotein (apo) A-I with a molecular weight (M r) of 26 kDa was first isolated from the plasma high density lipoproteins of an atypical Japanese eel (Anguilla japonica). Interestingly, this eel contained a very small amount of intact apoA-I (M r28 kDa) in the plasma, although serine protease inhibitors were present throughout the plasma preparation. The N-terminal sequence of 20 amino acids in truncated apoA-I was completely identical with that of intact apoA-I. Another apolipoprotein with M r28 kDa, whose N-terminal amino acid sequence differed from apoA-I, was also found in high density lipoprotein and low density lipoprotein. The apolipoprotein profiles of Japanese eel plasma appear to be complicated.
Keywords:Japanese eel  Anguilla japonica  apolipoprotein A-I truncation  plasma lipoproteins  N-terminal amino acid sequence
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