Identification of a Novel Casbane-Type Diterpene Phytoalexin,ent-10-Oxodepressin,from Rice Leaves |
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Abstract: | (+)-Haedoxan A, an insecticidal sesquilignan, inhibited the specific binding of the noncompetitive GABA antagonist 35S]t-butylbicyclophosphorothionate (TBPS) to rat brain membranes in concentration-dependent and noncompetitive manners. The data show haedoxan’s interaction with a site coupled to the TBPS-binding site on the GABAA receptor in rat brain, while the physiological significance of the interaction remains to be discovered. |
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Keywords: | phytoalexin rice blast fungus diterpene casbane |
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