Aplysiallene,a New Bromoallene as an Na,K-ATPase Inhibitor from the Sea Hare,Aplysia kurodai

A new bromoallene metabolite, named aplysiallene, was isolated from the Japanese sea hare, Aplysia kurodai, as an Na,K-ATPase inhibitor. Its structure was elucidated by spectroscopic methods. The known metabolites, laurinterol and debromolaurinterol, isolated from this animal were also evaluated for their Na,K-ATPase inhibitory activity.