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Achillinin A,a Cytotoxic Guaianolide from the Flower of Yarrow,Achillea millefolium
Abstract:Achillinin A (2β,3β-epoxy-1α,4β,10α-trihydroxyguai-11(13)-en-12,6α-olide, 1), a new guaianolide isolated from the flower of Achillea millefolium, exhibited potential antiproliferative activity to A549, RERF-LC-kj and QG-90 cells with 50% inhibitory concentration (IC50) values of 5.8, 10 and 0.31 μM, respectively.
Keywords:Achillea millefolium  flower  guaianolide  isolation
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