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First Evidence for Homologous Recombination-mediated Large DNA Inversion on the Bacillus subtilis 168 Chromosome |
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| Abstract: | A Bacillus subtilis 168 strain carrying an inversion of about 1600kb-long chromosomal DNA was isolated. Physical and genetic analyses demonstrated that the inversion was generated as a result of homologous recombination between two homologous sequences integrated at the met and leuB loci. This is the first clear evidence of a large stable chromosomal inversion induced by homologous recombination in B. subtilis. |
| Keywords: | polychlorinated dibenzo-p-dioxins (PCDDs) polychlorinated dibenzofurans (PCDFs) coplanar PCBs (Co-PCBs) maternal samples distribution |