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Lipase-catalyzed Optical Resolution of 2,2,2-Trifluoro-1-(1-naphthyl)ethanol |
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| Abstract: | The optical resolution of the title compound (TFNE) was achieved by lipase LIP-catalyzed enantioselective acetylation (E value > 100) with vinyl acetate in octane. S-TFNE acetate and R-TFNE were obtained with high optical purity. |
| Keywords: | castanospermine deoxynojirimycin N-glycan glycosidase inhibitors Raphanus sativus |