Thermal Stability of Cytochrome c 5 of Pressure-Sensitive Shewanella livingstonensis

Cytochrome c ₅ of pressure-sensitive Shewanella livingstonensis (SL cytc ₅) exhibits lower thermal stability than a highly homologous counterpart of pressure-tolerant Shewanella violacea. This stability difference is due to an enthalpic effect that can be attributed to the amino acid residue at position 50 (Leu or Lys). These cytc ₅ proteins are appropriate materials for understanding the protein stability mechanism.