A novel bicyclic ketolide derivative |
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| Authors: | Zhao Ying You Qidong Shen Wenbin |
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| Affiliation: | Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, Jiangsu 210009, PR China. |
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| Abstract: | A novel bicyclic ketolide derivative, 10,11-didehydro-11-deoxy-3-O-descladinosyl-6-O-methyl-3-oxo-8,9-anhydroerythromycin 9,12-hemiacetal(6) was obtained from 3-O-descladinosyl-6-O-methylerythromycin 2'-acetate. The structure and stereochemistry of this novel compound were elucidated and established by NMR and X-ray crystallography. |
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