Enantioselective cyanosilylation of ketones catalyzed by recyclable polymeric and dimeric Mn(III) salen complexes at room temperature |
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Authors: | Khan Noor-Ul H Agrawal Santosh Kureshy Rukhsana I Abdi Sayed H R Prathap K Jeya Jasra Raksh V |
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Affiliation: | Discipline of Inorganic Materials and Catalysis, Central Salt and Marine Chemicals Research Institute (CSMCRI), Bhavnagar, Gujarat, India. khan2593@yahoo.co.in |
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Abstract: | Recyclable polymeric 1 and dimeric 2 chiral Mn(III) salen complexes catalyzed enantioselective cyanosilylation of various ketones in the presence of triphenylphosphine oxide as an additive proceeded smoothly at room temperature, providing excellent yields (up to 98%) and enantiomeric excess (up to 86%) of respective cyanohydrin trimethylsilyl ether. For most of the substrates, the Catalyst 1 showed slightly better reactivity and enantioselecitivity than the Catalyst 2 nevertheless both the catalysts were easily recovered and reused four times with the retention of their efficiency. |
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Keywords: | cyanosilylation recyclable ketone Mn(III) salen complexes TMSCN |
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