Parafollicular cells of rabbit thyroid store both calcitonin and somatostatin and resemble gut D cells ultrastructurally |
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| Authors: | R. Buffa J. A. Chayvialle P. Fontana L. Usellini C. Capella E. Solcia |
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| Affiliation: | (1) Histopathology, Histochemistry and Ultrastructure Centre, Institute of Pathologic Anatomy, The University of Pavia, Via Forlanini 16, I-27100 Pavia, Italy;(2) ISERM, Hôpital Edouard-Herriot, Lyon, France |
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| Abstract: | Summary Both calcitonin and somatostatin have been detected immunohistochemically in rabbit parafollicular cells; only calcitonin has been found in the same cells of the dog, guinea-pig and man. Large amounts of a peptide radioimmunochemically identical with synthetic somatostatin have been detected in extracts of rabbit thyroid. The ultrastructural and staining features of rabbit parafollicular cells differ from those of parafollicular cells in other species, while resembling in part those of somatostatin D cells scattered in the rabbit stomach.Supported in part by grants from the Italian Ministero della Pubblica Istruzione and Consiglio Nazionale delle Ricerche |
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