损毁成体鸽下丘脑腹内侧核对神经元增生的影响

本实验应用（＾３Ｈ）放射自显影和免疫组织化学方法首次报道了高等脊椎动物成体鸟脑损伤引起神经元增生的观察结果。电损毁非鸣禽成体环鸽下丘脑腹内侧核后能引起端脑外侧室带区中（＾３Ｈ）标记细胞的大量增生和在端脑尾部ＬＶＺ中的特异性分布。

THE EFFECT OF LESION OF NUCLEUS VENTROMEDIALIS HYPOTHALAMI ON NEUROGENESIS IN ADULT RING DOVES

In the present study the effects of lesion hypothalami ventromedialis nucleus(VMN) of ring dove (Streptopelia Risoria ) on neurogenesis regarding the lesion-induced change of distribution of proliferating cells in the lateral ventricular zone (LVZ) and new neurons in the non-ventricular zone (VZ) were studied by using 3H] thymidineautoradiographicand immunohistochemistry methods. The results showed that such lesion not only induced significant increase of neurogenesis in telencephalon (up to,1. 62 times of that of the intact doves), but also altered distribution patterns of the newborn neurons. Many of the new neurons confined in neostriatum medians and pars caudalis of telencephalon, where the crate of neurogenesis in intact dove is very low. Such kinds of neurogenesis in the birds with brain lesions may be region-dependent and somewhat underlie brain repair and alteration of endocrine function after brain injury.