Novel intertypic recombinants of epstein-barr virus in the chinese population |
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| Authors: | Midgley R S Blake N W Yao Q Y Croom-Carter D Cheung S T Leung S F Chan A T Johnson P J Huang D Rickinson A B Lee S P |
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| Affiliation: | CRC Institute for Cancer Studies, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom. |
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| Abstract: | Among 34 Epstein-Barr virus isolates from nonimmunocompromised Chinese donors, we identified three intertypic recombinants with type 1 sequences at the EBNA2 locus and type 2 sequences at some or all of the EBNA3A, -3B, and -3C loci. These appear to have arisen from independent, evolutionarily recent recombination events; such events may be commoner in nonimmunocompromised populations than hitherto imagined. |
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