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Live-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane
Authors:Yong Yang  Joy Wolfram  Jianliang Shen  Yuliang Zhao  Xiaohong Fang  Haifa Shen  Mauro Ferrari
Affiliation:1. Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA;2. CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience & Technology of China, Beijing 100190, China;3. Institute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100049, China;4. Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Key Laboratory of Molecular Nanostructures and Nanotechnology, Chinese Academy of Sciences, Beijing 100190, China;5. Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA;6. Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA
Abstract:
Keywords:SMAD4   Membrane docking   Single-molecule fluorescence imaging   Clathrin   Caveolin-1
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