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枣庄市2008年麻疹减毒活疫苗强化免疫效果评价
引用本文:李夫国,李明军.枣庄市2008年麻疹减毒活疫苗强化免疫效果评价[J].微生物学免疫学进展,2011,39(2):29-32.
作者姓名:李夫国  李明军
作者单位:1. 枣庄市疾病预防控制中心,枣庄,277101
2. 枣庄市山亭区疾病预防控制中心,枣庄,277200
摘    要:为了评价枣庄市麻疹疫苗(MV)强化免疫的效果,于2008年在所辖区开展了流行病学调查、麻疹血清学监测和费用-效益分析等,对MV强化免疫进行了评价。枣庄市麻疹年平均报告发病率在强化免疫前为14.1/10万,对1-6岁儿童开展MV强化免疫后,2010年麻疹发病率为0.8/10万,降低了93.5%;1-6岁儿童麻疹发病构成,强化免疫前为39.87%,强化免疫后为25.90%,大大减少了5岁以下儿童的麻疹发病;强化免疫后,1-6岁儿童麻疹抗体阳性率为99.3%,抗体几何平均滴度(GMT)从强化免疫前的1∶563.0增长到强化免疫后的1∶814.9。开展MV强化免疫费用-效益比值为1∶2.23~1∶3.12。开展MV初始化强化免疫是加速麻疹控制最有效的措施之一。

关 键 词:麻疹减毒活疫苗  强化免疫  效果评价

Measles mass campaign experience and effect evaluation on measles vaccine in Zaozhuang city in 2008
LI Fu-guo,LI Ming-jun.Measles mass campaign experience and effect evaluation on measles vaccine in Zaozhuang city in 2008[J].Progress In Microbiology and Immunology,2011,39(2):29-32.
Authors:LI Fu-guo  LI Ming-jun
Institution:LI Fu-guo,LI Ming-jun(1 Center of Disease Prevention and Control of Zaozhuang city,Zaozhuang 277101,China,2 Center of Disease Prevention and Control of Shanting District,Zaozhuang city,Zaozhuang 277200,China)
Abstract:The measles supplementary immunizations had been carried out in Zaozhuang City in Dec.2008.For evaluating the effect of measles catching-up vaccination campaigns in Zaozhuang,the epidemiological investigation,measles antibody surveillance and cost-benefit analysis of the vaccination campaigns were carried out.The measles incidence in 2010 is 0.8/100 000,reduced by 93.5%,as compared with 14.1/100 000 before the campaign in the children aged 1-6 years.The measles proportions in the children aged 1-6 years of ...
Keywords:Measles vaccine(MV)  Measles mass campaign  Effect evaluation  
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