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Antioxidant,antibacterial and cytotoxic potential of silver nanoparticles synthesized using terpenes rich extract of Lantana camara L. leaves
Authors:Patil Shriniwas P  Kumbhar Subhash T
Institution:1. Department of Pharmacognosy, SCES’s Indira College of Pharmacy, Pune, India;2. Department of Pharmacology, SCES’s Indira College of Pharmacy, Pune, India
Abstract:Several attempts have been made for green synthesis of silver nanoparticles (AgNPs) using different plant extracts. Present study revealed that, antioxidant, antibacterial and cytotoxic AgNPs were synthesized using terpenes-rich extract (TRE) of environmentally notorious Lantana camara L. leaves. AgNPs were characterized by advanced techniques like UV–Visible and Infra red spectroscopy; XRD, SEM techniques as terpenes coated sphere shaped NPs with average diameter 425 nm. Further, on evaluation, AgNPs were found to exhibit dose – dependent antioxidant potential, good to moderate antibacterial activity against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa; and toxicity on Brine shrimp (A. salinanauplii) with LD50 value 514.50 µg/ml.
Keywords:Terpenes-rich extract  Silver nanoparticles  Antioxidant  Antibacterial  Brine shrimp cytotoxicity
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