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The Disease-associated r(GGGGCC)n Repeat from the C9orf72 Gene Forms Tract Length-dependent Uni- and Multimolecular RNA G-quadruplex Structures |
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| Authors: | Kaalak Reddy Bita Zamiri Sabrina Y R Stanley Robert B Macgregor Jr Christopher E Pearson |
| Institution: | From the ‡Program of Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.;the §Program of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 1L7, Canada, and ;the ¶Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada |
| Abstract: | |
| Keywords: | Amyotrophic Lateral Sclerosis (Lou Gehrig Disease) Neurodegenerative Diseases Nucleotide Repeat Disease RNA Structure RNA-Protein Interaction ALS-FTD C9ORF72 G-quadruplex Multimolecular Translation |